SP-D Products

Description

Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular head regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages. The serum concentration is 88 ng/ml in healthy individuals (2).

Bioinformatics

Entrez	6441 Human
Uniprot	AAH22318 Human AAH22318.1 Human NM_003019 Human P35247 Human
Product By Gene ID	6441
Alternate Names	COLEC7collectin-7 collectin 7 Collectin-7 Lung surfactant protein D PSPD PSP-D SFTP4pulmonary surfactant-associated protein D SP-Dpulmonary surfactant apoprotein surfactant protein D surfactant, pulmonary-associated protein D surfactant-associated protein, pulmonary 4

Research Areas for SP-D

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Cell Cycle and Replication