SorLA Products

Antibodies
SorLA Antibody [Unconjugated] ...
SorLA Antibody [Unconjugated]
AF5699
Species: Hu, Mu
Applications: WB, IHC
Host: Sheep Polyclonal
SorLA Antibody (3B6B11)
SorLA Antibody (3B6B11)
NBP1-28882
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Mouse Monoclonal
SorLA Antibody (525122)
SorLA Antibody (525122)
MAB5699
Species: Hu
Applications: IHC
Host: Mouse Monoclonal
Proteins
SorLA Partial Recombinant Pro ...
SorLA Partial Recombinant Protein
H00006653-Q01
Species: Hu
Applications: WB, ELISA, PA
SorLA Recombinant Protein Ant ...
SorLA Recombinant Protein Antigen
NBP2-38177PEP
Species: Hu
Applications: AC
RNAi
SorLA RNAi
SorLA RNAi
H00006653-R01
Species: Hu

Description

SORL1 (sortilin-related receptor, L A repeats containing) also known as sorting protein-related receptor containing LDLR class A (SorLA), is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. The gene encoding for the protein maps to chromosome 8p23.1. SorLA is expressed mainly in brain (cerebral cortex, cerebellum and the occipital pole), but can also be found in liver, spinal cord, kidney, testis and pancreas.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Mouse
Product By Gene ID 6653
Alternate Names
  • Sorting protein-related receptor containing LDLR class A repeats
  • sortilin-related receptor
  • Low-density lipoprotein receptor relative with 11 ligand-binding repeats
  • mosaic protein LR11
  • SorLA
  • FLJ39258
  • sortilin-related receptor, L(DLR class) A repeats-containing
  • FLJ21930
  • gp250
  • chromosome 11 open reading frame 32
  • LRP9
  • SorLA-1SORLA
  • LR11LDLR relative with 11 ligand-binding repeats
  • C11orf32
  • sortilin-related receptor, L(DLR class) A repeats containing

Bioinformatics Tool for SorLA

Discover related pathways, diseases and genes to SorLA. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.