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SOCS-7/Nck/NAP4 Products

Antibodies
Proteins
SOCS-7/Nck/NAP4 Recombinant P ...
SOCS-7/Nck/NAP4 Recombinant Protei...
NBP2-13363PEP
Species: Hu
Applications: AC

Description

Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins

Bioinformatics

Product By Gene ID 30837
Alternate Names
  • NAP4
  • NAP-4
  • NAP4SOCS-7
  • Nck
  • Nck, Ash and phospholipase C binding protein
  • Nck, Ash and phospholipase C gamma-binding protein
  • NCKAP4
  • Nck-associated protein 4
  • SOCS6
  • SOCS7
  • SOCS-7
  • suppressor of cytokine signaling 7

Research Areas for SOCS-7/Nck/NAP4

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction