SIRP alpha/CD172a Products

Antibodies
SIRP alpha/CD172a Antibody (7 ...
SIRP alpha/CD172a Antibody (772734)
MAB7307
Species: Rt
Applications: WB, Flow, CyTOF-ready, Neut
Host: Mouse Monoclonal
SIRP alpha/CD172a Antibody [U ...
SIRP alpha/CD172a Antibody [Unconj...
AF4546
Species: Hu
Applications: WB, Simple Western
Host: Sheep Polyclonal
Lysates
SIRP alpha/CD172a Overexpress ...
SIRP alpha/CD172a Overexpression L...
NBL1-15971
Species: Hu
Applications: WB
SIRP alpha/CD172a Overexpress ...
SIRP alpha/CD172a Overexpression L...
NBP2-05765
Species: Hu
Applications: WB
SIRP alpha/CD172a Overexpress ...
SIRP alpha/CD172a Overexpression L...
NBP2-11199
Species: Hu
Applications: WB
Proteins
Recombinant Human SIRP alpha ...
Recombinant Human SIRP alpha Fc Bi...
BT4546
Species: Hu
Applications: BA
Conjugate Catalog # Availability Size Price
Recombinant Cynomolgus Monkey ...
Recombinant Cynomolgus Monkey SIRP...
9519-SA
Species: Cm
Applications: BA
Recombinant Human SIRP alpha/ ...
Recombinant Human SIRP alpha/CD172...
9378-SA
Species: Hu
Applications: BA
RNAi
SIRP alpha/CD172a RNAi
SIRP alpha/CD172a RNAi
H00140885-R01
Species: Hu
Applications: RNAi, RNAi SP
SIRP alpha/CD172a RNAi
SIRP alpha/CD172a RNAi
H00140885-R02
Species: Hu
Applications: RNAi, RNAi SP
SIRP alpha/CD172a RNAi
SIRP alpha/CD172a RNAi
H00140885-R03
Species: Hu
Applications: RNAi, RNAi SP

Description

Protein tyrosine phosphatases (PTPases) SHP-1 and SHP-2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP-2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP-2 associated glycoprotein was recently cloned from human, rat, mouse and cattle by several labs and was designated SIRPa (1), SHPS-1 (2,3), MyD-1 (4), BIT (5,6) and p84 (7). SIRPa is a new gene family containing at least fifteen members. SIRPa is a substrate of many activated tyrosine kinases such as insulin receptor, EGFR, PDGFR and src, and a specific docking protein for SHP-2 (1,2,5,8). SIRPa has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes (1,2,5,8).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Rat
Product By Gene ID 140885
Alternate Names
  • Signal-regulatory protein alpha-3
  • SIRPalpha2
  • Signal-regulatory protein alpha-2
  • SIRPalpha
  • Signal-regulatory protein alpha-1
  • SIRP-ALPHA-1
  • SHP substrate 1
  • CD172a
  • p84
  • CD172 antigen-like family member A
  • CD172a antigen
  • PTPNS1
  • Brain Ig-like molecule with tyrosine-based activation motifs
  • MyD-1 antigen
  • Sirp-alpha-3
  • Macrophage fusion receptor
  • Sirp-alpha-2
  • Inhibitory receptor SHPS-1
  • Sirp-alpha-1
  • SHPS-1
  • MYD1
  • P84
  • Bit
  • MYD-1
  • SIRPtyrosine-protein phosphatase non-receptor type substrate 1
  • MFRtyrosine phosphatase SHP substrate 1
  • BITbrain-immunoglobulin-like molecule with tyrosine-based activation motifs
  • SHPS1CD172A
  • protein tyrosine phosphatase, non-receptor type substrate 1
  • signal-regulatory protein alpha

Research Areas for SIRP alpha/CD172a

Find related products by research area and learn more about each of the different research areas below.

GPCR
Protein Phosphatase
Signal Transduction

PTMs for SIRP alpha/CD172a

Learn more about PTMs related to SIRP alpha/CD172a.

Phosphorylation
Dephosphorylation
Glycosylation
Biotinylation
Deglycosylation

Bioinformatics Tool for SIRP alpha/CD172a

Discover related pathways, diseases and genes to SIRP alpha/CD172a. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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