Species: Hu, Mu, Rt, Bv, Ca
Applications: ELISA, ICC/IF, IP
Host: Goat Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Rt, Bv, Pm, RM, Xp, Ze
Applications: WB, Func, IHC, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Description
SIAH1 encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
Bioinformatics
| Entrez |
Rat
Mouse
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
6477 |
| Alternate Names |
- E3 ubiquitin-protein ligase SIAH1
- EC 6.3.2
- EC 6.3.2.-
- FLJ08065
- hSIAH1
- HUMSIAH
- seven in absentia homolog 1 (Drosophila)
- Seven in absentia homolog 1
- Siah-1
- siah-1
- SIAH1A
- Siah-1a
- siah-1a
|
