Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IP, MA
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Mouse Monoclonal
Description
Function: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.; Subcellular location: Cytoplasm. Cell junction synapse. Cell junction synapse postsynaptic cell membrane postsynaptic density. Note: Postsynaptic density of neuronal cells. Extends into the region subjacent to the PSD.; Tissue specificity: Widely expressed in brain.
Bioinformatics
| Entrez |
Human
Mouse
Rat
|
| Uniprot |
Human
|
| Product By Gene ID |
85358 |
| Alternate Names |
- DEL22q13.3
- KIAA1650proline rich synapse associated protein 2
- Proline-rich synapse-associated protein 2
- prosap2
- PSAP2SH3 and multiple ankyrin repeat domains protein 3
- SH3 and multiple ankyrin repeat domains 3
- shank postsynaptic density protein
- Shank3
- SPANK-2
|
Research Areas for SHANK3
Find related products by research area and learn more about each of the different research areas below.
Neuroscience
