SH2B2 Products

SH2B2 Antibody
SH2B2 Antibody
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
SH2B2 Antibody
SH2B2 Antibody
Species: Mu
Applications: WB
Host: Rabbit Polyclonal
Recombinant Human SH2B2 Prote ...
Recombinant Human SH2B2 Protein
Species: Hu
Applications: WB, ELISA, PA, AP
SH2B2 Recombinant Protein Ant ...
SH2B2 Recombinant Protein Antigen
Species: Hu
Applications: AC


APS (adapter protein with Pleckstrin homology and Src homology 2 domains) is a member of the Lnk family, an adapter protein that is involved in B cell signaling, insulin signaling and cytoskeletal reorganization. A PH and an SH2 domain containing adapter protein that links activated tyrosine kinases to signaling pathways. It is tyrosine phosphorylated by JAK2, KIT and other kinases during B cell receptor stimulation of many different cytokines, chemokines and leukokines. APS has been shown to inhibit the JAK STAT pathway in collaboration with cCbl.


Entrez Human
Uniprot Human
Product By Gene ID 10603
Alternate Names
  • SH2B adapter protein 2
  • adaptor protein with pleckstrin homology and src homology 2 domains
  • SH2 and PH domain-containing adapter protein APS
  • APSAdapter protein with pleckstrin homology and Src homology 2 domains
  • SH2B adaptor protein 2

PTMs for SH2B2

Learn more about PTMs related to SH2B2.


Bioinformatics Tool for SH2B2

Discover related pathways, diseases and genes to SH2B2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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