Serpin A5/Protein C Inhibitor Products

Serpin A5/Protein C Inhibitor ...
Serpin A5/Protein C Inhibitor Anti...
Species: Mu
Applications: WB
Host: Rat Monoclonal
Formulation Catalog # Availability Price  
Serpin A5/Protein C Inhibitor ...
Serpin A5/Protein C Inhibitor Over...
Species: Hu
Applications: WB
Recombinant Human Serpin A5 P ...
Recombinant Human Serpin A5 Protei...
Species: Hu
Applications: Inhibition Activity
Formulation Catalog # Availability Price  


PAI-1, PAI-2 and PAI-3 (plasminogen activator inhibitor-1, -2 and -3) are members of the serpin serine proteinase inhibitor family. PAI-1 and PAI-2 regulate uPA (urokinase-type plasminogen activator) and TPA (tissue plasminogen activator), resulting in the inhibition of proteolytic activity. Members of the serpin family generally complex with their target proteinases, then disassociate slowly into cleaved species that fold into stable inactive forms. PAI-1 can fold into the inactive state without cleavage resulting in the latent form of PAI-1. Activity can be restored to the latent form of PAI-1 through denaturation and renaturation. PAI-2 occurs in secreted and cytosolic forms through facultative polypeptide translocation. PAI-3 inhibits plasminogen activators as well as activated protein C. PAI-3 is secreted in plasma, but is also expressed in liver.


Entrez Human
Uniprot Human
Product By Gene ID 5104
Alternate Names
  • Serpin A5
  • Plasminogen activator inhibitor 3
  • Protein C inhibitor
  • Acrosomal serine protease inhibitor
  • plasminogen activator inhibitor-3
  • antitrypsin), member 5
  • serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase
  • PCIplasminogen activator inhibitor III
  • PROCIplasma serine protease inhibitor
  • PAI-3
  • member 5
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)

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