SENP6 Products

Antibodies
SENP6 Antibody (4B7)
SENP6 Antibody (4B7)
H00026054-M01
Species: Hu, Mu
Applications: WB, ELISA, Flow, IHC, IHC-P
Host: Mouse Monoclonal
SENP6 Antibody
SENP6 Antibody
NBP1-82958
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
SENP6 Antibody
SENP6 Antibody
NBP1-00238
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Lysates
SENP6 Overexpression Lysate ( ...
SENP6 Overexpression Lysate (Native)
NBP2-07141
Applications: WB
Proteins
SENP6 Partial Recombinant Pro ...
SENP6 Partial Recombinant Protein
H00026054-Q01
Species: Hu
Applications: WB, ELISA, PA
SENP6 Recombinant Protein Ant ...
SENP6 Recombinant Protein Antigen
NBP1-82958PEP
Species: Hu
Applications: AC
RNAi
SENP6 RNAi
SENP6 RNAi
H00026054-R01
Species: Hu
Applications: RNAi, RNAi SP
SENP6 RNAi
SENP6 RNAi
H00026054-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000 [PubMed 10799485]).[supplied by OMIM]

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 26054
Alternate Names
  • EC 3.4.22.-
  • SUMO-1-specific protease 1
  • sentrin-specific protease 6
  • Sentrin/SUMO-specific protease SENP6
  • SUMO1/sentrin specific protease 6
  • SSP1KIAA0389
  • KIAA0797FLJ11887
  • SUSP1FLJ11355
  • SUMO1/sentrin specific peptidase 6,2810017C20Rik

PTMs for SENP6

Learn more about PTMs related to SENP6.

Sumoylation
Cleavage
Phosphorylation
Acetylation

Bioinformatics Tool for SENP6

Discover related pathways, diseases and genes to SENP6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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