Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
SAP30L is a novel TGF- beta up-regulated mRNA species, the Sin3-associated protein 30-like, SAP30L has been identified. The predicted nuclear localization signal of SAP30L is sufficient for nuclear transport of the protein although mutating it does not completely remove SAP30L from the nuclei. By reason of its nuclear localization and close homology to SAP30 it is thought that SAP30L might have a role in recruiting the Sin3-histone deacetylase complex to specific co-repressor complexes in response to TGF-beta, leading to the silencing of proliferation-driving genes in the differentiating intestinal epithelial cells.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human |
Product By Gene ID |
79685 |
Alternate Names |
- DKFZp667L2214
- FLJ11526
- FLJ36497
- HCV non-structural protein 4A-transactivated protein 2
- histone deacetylase complex subunit SAP30L
- NS4ATP2FLJ23595
- SAP30-like
- Sin3 corepressor complex subunit SAP30L
- Sin3A associated protein p30-like
- Sin3-associated protein p30-like
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