SAP30L Products

Description

SAP30L is a novel TGF- beta up-regulated mRNA species, the Sin3-associated protein 30-like, SAP30L has been identified. The predicted nuclear localization signal of SAP30L is sufficient for nuclear transport of the protein although mutating it does not completely remove SAP30L from the nuclei. By reason of its nuclear localization and close homology to SAP30 it is thought that SAP30L might have a role in recruiting the Sin3-histone deacetylase complex to specific co-repressor complexes in response to TGF-beta, leading to the silencing of proliferation-driving genes in the differentiating intestinal epithelial cells.

Bioinformatics

Entrez	79685 Human
Uniprot	NM_024632 Human NP_078908.1 Human
Product By Gene ID	79685
Alternate Names	HCV non-structural protein 4A-transactivated protein 2 Sin3A associated protein p30-like Sin3-associated protein p30-like histone deacetylase complex subunit SAP30L Sin3 corepressor complex subunit SAP30L FLJ36497 FLJ11526 NS4ATP2FLJ23595 DKFZp667L2214 SAP30-like

Diseases related to SAP30L

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Polycystic Kidney Diseases
Muscular Fasciculation
Kidney Diseases
Heart Failure

Pathways for SAP30L

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Localization
Transport
Regulation Of Gene Expression
Chromatin Remodeling
Cell Proliferation
Gene Silencing
Cell Development
Dna Repair
Nuclear Transport
Mrna Splicing
Cell Cycle
Histone Acetylation
Cell Differentiation
Epithelial Cell Differentiation
Epithelial Cell Proliferation

PTMs for SAP30L

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Deacetylation

Bioinformatics Tool for SAP30L

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