RUNX1T1/ETO Products

Antibodies
RUNX1T1/ETO Antibody (5A12)
RUNX1T1/ETO Antibody (5A12)
H00000862-M01
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
RUNX1T1/ETO Antibody (1H1)
RUNX1T1/ETO Antibody (1H1)
NBP2-02023
Species: Hu
Applications: WB, ICC/IF
Host: Mouse Monoclonal
RUNX1T1/ETO Antibody
RUNX1T1/ETO Antibody
NBP2-55747
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Lysates
RUNX1T1/ETO Overexpression Ly ...
RUNX1T1/ETO Overexpression Lysate ...
H00000862-T01
Species: Hu
Applications: WB
RUNX1T1/ETO Overexpression Ly ...
RUNX1T1/ETO Overexpression Lysate ...
NBL1-15625
Applications: WB
RUNX1T1/ETO Overexpression Ly ...
RUNX1T1/ETO Overexpression Lysate ...
NBL1-15626
Applications: WB
Proteins
Recombinant Human RUNX1T1/ETO ...
Recombinant Human RUNX1T1/ETO Protein
H00000862-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human RUNX1T1/ETO ...
Recombinant Human RUNX1T1/ETO Protein
H00000862-P01
Species: Hu
Applications: WB, ELISA, PA
RUNX1T1/ETO Recombinant Prote ...
RUNX1T1/ETO Recombinant Protein An...
NBP2-55747PEP
Species: Hu
Applications: AC
RNAi
RUNX1T1/ETO RNAi
RUNX1T1/ETO RNAi
H00000862-R02
Species: Hu
Applications: RNAi, RNAi SP
RUNX1T1/ETO RNAi
RUNX1T1/ETO RNAi
H00000862-R01
Species: Hu
Applications: RNAi, RNAi SP
RUNX1T1/ETO RNAi
RUNX1T1/ETO RNAi
H00000862-R03
Species: Hu
Applications: RNAi, RNAi SP

Description

RUNX1T1 / ETO is encoded by this gene is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Several transcript variants encoding multiple isoforms have been found for this gene.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 862
Alternate Names
  • Zinc finger MYND domain-containing protein 2
  • Protein MTG8
  • Eight twenty one protein
  • Protein ETO
  • core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclinD-related
  • CBFA2T1Cyclin-D-related protein
  • AML1T1protein CBFA2T1
  • ZMYND2myeloid translocation gene on 8q22
  • MTG8acute myelogenous leukemia 1 translocation 1, cyclin-D related
  • CDRMGC2796
  • ETOFLJ33145
  • DKFZp564B213
  • runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

PTMs for RUNX1T1/ETO

Learn more about PTMs related to RUNX1T1/ETO.

Cleavage
Methylation
Acetylation
Phosphorylation
Demethylation

Bioinformatics Tool for RUNX1T1/ETO

Discover related pathways, diseases and genes to RUNX1T1/ETO. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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