RNF40 Products

Description

RNF40 is encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.

Bioinformatics

Entrez	9810 Human
Uniprot	O75150 Human NM_014771 Human NP_055586 Human NP_055586.1 Human
Product By Gene ID	9810
Alternate Names	EC 6.3.2,95 kDa retinoblastoma protein binding protein BRE1-B EC 6.3.2.- 95 kDa retinoblastoma-associated protein Rb-associated protein STARING RBP95E3 ubiquitin-protein ligase BRE1B KIAA0661BRE1 E3 ubiquitin ligase homolog B BRE1BMGC13051 ring finger protein 40DKFZp686K191

Diseases related to RNF40

Discover more about diseases related to RNF40.

Neoplasms
Malignant Neoplasms
Carcinoma
Genomic Instability
Retinoblastoma
Exposure To Ionizing Radiation
Tumor Progression
Malignant Neoplasm Of Breast
Seminoma
Glioma
Gastrointestinal Neoplasms
Head And Neck Carcinoma
Testicular Seminoma
Carcinogenesis
Hypokinesia
Neoplasms, Hormone-dependent
Head And Neck Neoplasms
Metastatic Prostate Cancer

Pathways for RNF40

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Methylation
Cell Cycle
Cell Growth
Cell Cycle Checkpoint
Cell Proliferation
Recombinational Repair
Gene Silencing
Stem Cell Differentiation
Cell Cycle Phase
Mrna 3'-end Processing
Histone Monoubiquitination
Dna Repair
Histone Mrna 3'-end Processing
Histone Modification
Cell Cycle Arrest
Double-strand Break Repair
Cell Division
Response To Ionizing Radiation
Cell Differentiation
Chromatin Organization

Research Areas for RNF40

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Chromatin Research
Vision
Zinc Finger

PTMs for RNF40

Learn more about PTMs related to RNF40.

Methylation
Phosphorylation
Ubiquitination
Acetylation
Reduction
Cleavage

Bioinformatics Tool for RNF40

Discover related pathways, diseases and genes to RNF40. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.