RNF12 Products

Description

RNF12 is encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be a ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Alternatively spliced transcript variants encoding the same protein have been reported.

Bioinformatics

Entrez	51132 Human
Uniprot	NP_057204 Human NP_057204.2 Human Q9NVW2 Human
Product By Gene ID	51132
Alternate Names	DKFZp686N06224 E3 ubiquitin-protein ligase RLIM E3 ubiquitin-protein ligase RNF12 EC 6.3.2 EC 6.3.2.- FLJ25923 FLJ41093 LIM domain-interacting RING finger protein MGC15161 NY-REN-43 Renal carcinoma antigen NY-REN-43 RING finger LIM domain-binding protein RING finger protein 12FLJ42887 ring finger protein, LIM domain interacting ring zinc finger LIM domain binding protein ring zinc finger protein NY-REN-43antigen R-LIM RNF12FLJ45986

Diseases related to RNF12

Discover more about diseases related to RNF12.

Malignant Neoplasms
Coughing
Whooping Cough Due To Unspecified Organism
Neoplasms
Tuberculosis
Tuberculosis, Pulmonary
Malignant Neoplasm Of Breast
Colonic Neoplasms
Communicable Diseases
Malignant Tumor Of Colon
Teratocarcinoma
Smallpox
Carcinogenesis
Osteosarcoma
Telomere Shortening
Nervousness
Pertussis
Mammary Neoplasms
Cell Transformation, Neoplastic

Pathways for RNF12

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Cell Proliferation
Neuron Differentiation
Dosage Compensation
Cell Migration
Gastrulation
Proteolysis
Mesoderm Formation
Regulation Of Gene Expression
Localization
Cytoskeleton Organization
Translation
Telomere Maintenance
Cell Growth
Wound Healing
Pathogenesis
Tissue Homeostasis
Oncogenesis

Research Areas for RNF12

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Zinc Finger

PTMs for RNF12

Learn more about PTMs related to RNF12.

Ubiquitination

Bioinformatics Tool for RNF12

Discover related pathways, diseases and genes to RNF12. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.