RFC5 Products

Description

The Replication factor C (RFC) heteropentamer includes RFC1, RFC2, RFC3, RFC4, and RFC5. The RFC heteropentamer is part of the multiprotein DNA replicase that functions to replicate DNA prior to cell division and repair DNA damage. RFC is the clamp loader ATPase associated with the DNA replicase. As the clamp loader, RFC uses ATP to recruit, open, and close the PCNA ring to link it to DNA for replication and repair. RFC5 is the 36kDa subunit of RFC that forms a core complex with RFC2 and RFC4 and can interact with the C-terminal region of PCNA. RFC5 is also known as replication factor C 36 kDa subunit RF-C 36 kDa subunit, RFC36, Activator 1 36 kDa subunit, A1 36 kDa subunit, and MGC1155.

Bioinformatics

Entrez	5985 Human
Uniprot	AAH13961 Human NM_007370 Human NP_031396 Human NP_031396.1 Human P40937 Human
Product By Gene ID	5985
Alternate Names	Activator 1 36 kDa subunit Activator 1 subunit 5,36.5 kD subunit MGC1155 replication factor C (activator 1) 5, 36.5kDa RF-C 36 kDa subunit RFC36replication factor C (activator 1) 5 (36.5kD)

Research Areas for RFC5

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
DNA Repair