RFC2 Products

Description

The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also called activator 1, is a protein complex consisting of five distinct subunits of 145, 40, 38, 37, and 36.5 kD. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP. Deletion of this gene has been associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]. Transcript Variant: This variant (2) lacks an in-frame coding segment, as compared to variant 1. The resulting shorter isoform (2) lacks an internal region, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Bioinformatics

Product By Gene ID	5982
Alternate Names	A1 40 kDa subunit A1 Activator 1 40 kDa subunit Activator 1 subunit 2 MGC3665 replication factor C (activator 1) 2, 40kDa replication factor C 2 Replication factor C 40 kDa subunit replication factor C subunit 2 RF-C 40 kDa subunit RFC40replication factor C (activator 1) 2 (40kD)

Research Areas for RFC2

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
DNA Repair