RelA/NFkB p65 Products

Antibodies
ELISA Kits
RelA/NFkB p65 ELISA Kit
RelA/NFkB p65 ELISA Kit
NBP2-29661
Species: Hu, Mu, Rt
Applications: ELISA, S-ELISA
Inhibitors
RelA/NFkB p65 [p Ser276] Inhi ...
RelA/NFkB p65 [p Ser276] Inhibitor...
NBP2-26505
Species: Hu, Mu, Rt, Bv, Ca, Ma
Applications: B/N, Func-Inh, In vivo
RelA/NFkB p65 [p Ser529, p Se ...
RelA/NFkB p65 [p Ser529, p Ser536]...
NBP2-29321
Species: Hu, Mu, Rt, Bv, Ca
Kits
RelA/NFkB p65 Assay Kit
RelA/NFkB p65 Assay Kit
KA1341
Applications: Func
RelA/NFkB p65 Assay Kit
RelA/NFkB p65 Assay Kit
KA1340
Applications: Func
Lysates
RelA/NFkB p65 Overexpression ...
RelA/NFkB p65 Overexpression Lysat...
NBL1-15276
Applications: WB
Proteins
RelA/NFkB p65 Recombinant Pro ...
RelA/NFkB p65 Recombinant Protein
NBP2-24987
RelA/NFkB p65 Recombinant Pro ...
RelA/NFkB p65 Recombinant Protein
H00005970-P01
Species: Hu
Applications: WB, ELISA, PA
RelA/NFkB p65 Recombinant Pro ...
RelA/NFkB p65 Recombinant Protein
H00005970-P02
Species: Hu
Applications: WB, ELISA, PA
RNAi
RelA/NFkB p65 RNAi
RelA/NFkB p65 RNAi
H00005970-R01
Species: Hu

Description

Nuclear factor B (NF-B) encompasses an important family of inducible transcriptional activators that regulate a wide variety of cellular and viral genes. The family members include p50, p52, p65 (RelA), c-Rel, and RelB. The Nf-kB p65 subunit, similar to two others in the B family, RelB and c-Rel, contains two transactivation domains in the C-terminal region of the protein. Association with inhibitory proteins of the I B family, retains NF- B in the cytoplasm. Degradation of IB proteins exposes the nuclear localization sequence (NLS), leading to nuclear translocation and subsequent binding of NF-B to DNA. In addition to the nuclear translocation and DNA binding, Nf-kB's transcriptional activity is also regulated by coactivators and corepressors in the nucleus. Interaction of p65 with coactivators; CREB-binding protein and p300, increases its transcriptional activity.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Mouse
Product By Gene ID 5970
Alternate Names
  • rela p65
  • nf kb p65
  • NF-kB p65
  • RelA
  • NFkB p65
  • Nuclear factor NF-kappa-B p65 subunit
  • v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappalight polypeptide gene enhancer in B-cells 3, p65
  • p65
  • NFKB3v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor ofkappa light polypeptide gene enhancer in B-cells 3 (p65))
  • Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3transcription factor p65
  • MGC131774
  • v-rel reticuloendotheliosis viral oncogene homolog A (avian)

Research Areas for RelA/NFkB p65

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Cell Biology
Immune System Diseases
Immunology
Innate Immunity
Neurodegeneration
Neuroscience
Phospho-Specific
Signal Transduction
Transcription Factors and Regulators

Bioinformatics Tool for RelA/NFkB p65

Discover related pathways, diseases and genes to RelA/NFkB p65. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related RelA/NFkB p65 Blog Posts

Check out the latest blog posts on RelA/NFkB p65.
NFkB3-p65: Say that three times fast!
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes such as inflammation, immunity, differentiation, cell growth, tumor genesis and apoptosis. Unlike the majority of transcription factors that reside in the nucleus...    Read more.
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