RBMS1 Products

Description

RBMS1 encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Multiple transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. Several of these were isolated by virtue of their binding to either strand of an upstream element of c-myc (MSSPs), or by phenotypic complementation of cdc2 and cdc13 mutants of yeast (scr2), or as a potential human repressor of HIV-1 and ILR-2 alpha promoter transcription (YC1). A pseudogene for this locus is found on chromosome 12.

Bioinformatics

Entrez	5937 Human
Uniprot	AAH12993 Human NM_002897 Human NM_016836 Human NP_058520 Human NP_058520.1 Human P29558 Human P29558-2 Human
Product By Gene ID	5937
Alternate Names	chromosome 2 open reading frame 12 DKFZp564H0764 HCC-4 MGC15146 MGC3331 MGC97258 MGC97270 MGC97282 MGC99543 MSSP1 MSSP-1 MSSP-2 MSSP-3 RNA binding motif, single stranded interacting protein 1 SCR2MGC70597 single-stranded-interacting protein 1 suppressor of cdc 2 (cdc13) with RNA binding motif 2