Hu, Rt, Canine, Guinea Pig, Primate, MouseApplications:
Applications: WB, IP, DirELISA
Host: Mouse Monoclonal
WB, ELISA, ICC/IFHost:
WB, ELISA, PA
Applications: WB, ELISA, PA
Applications: B/N, Ctrl
Retinoids can reverse various premalignant lesions as well as prevent some second primary tumors. The effects of retinoids are regulated by retinoic acid receptors (RAR) and retinoid X receptors, which act as ligand-activated transcription factors. Ligand-dependent transcriptional activation of RARs is a multistep process that ends with the formation of a multimeric co-activator complex on regulated promoters (1,2). Loss of RAR-beta expression and the accumulation of p53 and Ki67 proteins may help in the early identification of esophageal cancer in high-risk populations (3).
Bioinformatics Tool for RAR beta/NR1B2
Discover related pathways, diseases and genes to RAR beta/NR1B2. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.