RAB8A Products

Antibodies
RAB8A Antibody (3G1)
RAB8A Antibody (3G1)
H00004218-M02
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
RAB8A Antibody
RAB8A Antibody
NB100-93433
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Lysates
RAB8A Overexpression Lysate ( ...
RAB8A Overexpression Lysate (Native)
NBL1-15090
Applications: WB
Proteins
Recombinant Human RAB8A Prote ...
Recombinant Human RAB8A Protein
H00004218-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human RAB8A Prote ...
Recombinant Human RAB8A Protein
H00004218-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
RAB8A RNAi
RAB8A RNAi
H00004218-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

RAB8A is encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 4218
Alternate Names
  • Oncogene c-mel
  • ras-related protein Rab-8A
  • mel transforming oncogene (derived from cell line NK14)
  • MELras-associated protein RAB8
  • RAB8mel transforming oncogene (RAB8 homolog)
  • mel transforming oncogene (derived from cell line NK14)- RAB8 homolog
  • RAB8A, member RAS oncogene family

Bioinformatics Tool for RAB8A

Discover related pathways, diseases and genes to RAB8A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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