Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Mu, Rt
Applications: WB, ELISA
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotidemodification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylatesynthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicingRNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty etal., 2007 (PubMed 17900615)).(supplied by OMIM)
Bioinformatics
| Entrez |
Human |
| Uniprot |
Human Human |
| Product By Gene ID |
150962 |
| Alternate Names |
- CCDC139
- coiled-coil domain containing 139
- Coiled-coil domain-containing protein 139
- DOBIMGC126729
- EC 5.4.99
- EC 5.4.99.-
- FLJ32312
- MGC126755
- pseudouridine synthase 10
- pseudouridylate synthase 10
- Psi55 synthase
- PUS1
- putative tRNA pseudouridine synthase Pus10
- tRNA pseudouridine 55 synthase
- tRNA pseudouridylate synthase
- tRNA-uridine isomerase
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