Species: Hu, Mu, Rt, Bv, Ca, Eq, Pm, Po, Pm, Pm
Applications: WB, Flow
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, MA
Host: Mouse Monoclonal
Species: Hu, Rt
Applications: WB, ELISA, Flow, IHC
Host: Goat Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
PU.1/Spi1 encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Bioinformatics
| Product By Gene ID |
6688 |
| Alternate Names |
- hematopoietic transcription factor PU.1
- OF
- PU.1
- SFPI1
- SFPI131 kDa transforming protein
- SPI-1 proto-oncogene
- SPI1
- Spi-1
- SPI-A
- spleen focus forming virus (SFFV) proviral integration oncogene spi1,31 kDa-transforming protein
- transcription factor PU.1
|
Research Areas for PU.1/Spi-1
Find related products by research area and learn more about each of the different research areas below.
Innate Immunity
