PTPN21 Products

Lysates
PTPN21 Overexpression Lysate ...
PTPN21 Overexpression Lysate (Native)
NBP2-07541
Applications: WB
RNAi
PTPN21 RNAi
PTPN21 RNAi
H00011099-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

PTPN21 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 11099
Alternate Names
  • EC 3.1.3.48
  • EC 3.1.3
  • Protein-tyrosine phosphatase D1
  • tyrosine-protein phosphatase non-receptor type 21
  • PTPRL10
  • PTPD1protein tyrosine phosphatase D1
  • dJ1175B15.2 (protein tyrosine phosphatase, non-receptor type 21)
  • protein tyrosine phosphatase, non-receptor type 21

Pathways for PTPN21

View related products by pathway and learn more about each of the pathways below.

Cell Adhesion
Sensitization
Cell Migration
Cell Motility
Receptor Recycling
Localization
Chondrocyte Differentiation

PTMs for PTPN21

Learn more about PTMs related to PTPN21.

Phosphorylation

Bioinformatics Tool for PTPN21

Discover related pathways, diseases and genes to PTPN21. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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