PTP4A1 Products

Description

The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells.

Bioinformatics

Entrez	7803 Human
Uniprot	NP_003454.1 Human
Product By Gene ID	7803
Alternate Names	EC 3.1.3.48 HH72 PRL1 PRL-1 PRL-1DKFZp779M0721 Protein tyrosine phosphatase IVA1 protein tyrosine phosphatase type IVA 1 protein tyrosine phosphatase type IVA protein 1 protein tyrosine phosphatase type IVA, member 1 Protein-tyrosine phosphatase 4a1 Protein-tyrosine phosphatase of regenerating liver 1 PTP(CAAX1) PTP(CAAXI) PTPCAAX1PRL1PTP(CAAX1)

Research Areas for PTP4A1

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Signal Transduction