PTP-MEG2/PTPN9 Products

Description

The protein encoded by the PTPN9 gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis. (provided by RefSeq)

Bioinformatics

Entrez	5780 Human
Uniprot	P43378 Human NP_002824.1 Human AAH10863 Human
Product By Gene ID	5780
Alternate Names	tyrosine-protein phosphatase non-receptor type 9 PTPase MEG2 PTPase-MEG2 Protein-tyrosine phosphatase MEG2 PTPMEG2 MEG2 EC 3.1.3.48 protein tyrosine phosphatase, non-receptor type 9

Diseases related to PTP-MEG2/PTPN9

Discover more about diseases related to PTP-MEG2/PTPN9.

Posttransfusion Purpura
Malignant Neoplasm Of Breast
Insulin Resistance
Malignant Neoplasms
Hyperglycemia
Mammary Neoplasms
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Lymphomatoid Papulosis
Carotid Artery Diseases
Infarction
Acute Basophilic Leukemia
Neoplasm Invasiveness
Cardiovascular Diseases
Hemorrhage
Cerebral Infarction
Polycythemia
Basophilic Leukemia
Innate Immune Response
Dental Plaque

Pathways for PTP-MEG2/PTPN9

View related products by pathway and learn more about each of the pathways below.

Localization
Vesicle Fusion
Phagocytosis
Secretion
Transport
Secretory Pathway
Immune Response
Cell Differentiation
Cell Growth
Vesicle Targeting
Intracellular Transport
Insulin Secretion
Glucose Homeostasis
Sensitization
Innate Immune Response
Regulated Secretory Pathway
Bone Development
Regulation Of Insulin Secretion
Lymphocyte Activation

PTMs for PTP-MEG2/PTPN9

Learn more about PTMs related to PTP-MEG2/PTPN9.

Phosphorylation
Dephosphorylation

Bioinformatics Tool for PTP-MEG2/PTPN9

Discover related pathways, diseases and genes to PTP-MEG2/PTPN9. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.