PTP epsilon Products

Antibodies
PTP epsilon Antibody (5F2)
PTP epsilon Antibody (5F2)
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
PTP epsilon Antibody
PTP epsilon Antibody
NBP1-87189
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PTP epsilon Antibody
PTP epsilon Antibody
NBP1-87190
Species: Hu, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PTP epsilon Overexpression Ly ...
PTP epsilon Overexpression Lysate ...
NBP2-05741
Applications: WB
PTP epsilon Overexpression Ly ...
PTP epsilon Overexpression Lysate ...
NBL1-14984
Applications: WB
Proteins
PTP epsilon Partial Recombina ...
PTP epsilon Partial Recombinant Pr...
H00005791-Q01
Species: Hu
Applications: WB, ELISA, PA
PTP epsilon Recombinant Prote ...
PTP epsilon Recombinant Protein An...
NBP1-87190PEP
Species: Hu
Applications: AC
PTP epsilon Recombinant Prote ...
PTP epsilon Recombinant Protein An...
NBP1-87189PEP
Species: Hu
Applications: AC
RNAi
PTP epsilon RNAi
PTP epsilon RNAi
H00005791-R05
Species: Hu
Applications: RNAi, RNAi SP
PTP epsilon RNAi
PTP epsilon RNAi
H00005791-R06
Species: Hu
Applications: RNAi, RNAi SP

Description

PTP epsilon, an R4 receptor protein tyrosine phosphatase, is composed of a short extracellular and two cyplasmic protein phosphatase domains and has been shown to affect neuronal differentiation, endothelial cell growth, vascular development, and possibly mammary tumor development. It has been shown that the cytosolic form of PTP epsilon can be induced by IL-1 and TNF alpha in humans and is a negative regulator of IL-6- and LIF-induced Jak-STAT kinase signaling in rats. Four alternatively spliced protein isoforms have been documented for PTP epsilon: a membrane form, a cytosolic form, the p65 form, which results from translation using an internal initiation codon, and the p67 form, which results from a specific proteolytic cleavage of wild-type PTP epsilon. PTP epsilon expression has been documented in human vascular endothelial cells, astrocytoma cells, and in IW32 erythroleukemia overexpressing p53. PTP epsilon expression has been documented in animal brain, breast, ganglion, heart, kidney, liver, lung, nerve, spinal cord, spleen, testis, and vessel. The membrane and cytosolic forms of PTP epsilon show different tissue expression patterns. ESTs have been isolated from numerous human tissue libraries, including normal human blood, brain, testis, and thyroid, and cancerous human blood, brain, breast, colon, embryo, head/neck, pancreas, and skin.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 5791
Alternate Names
  • FLJ58245
  • R-PTP-epsilon
  • FLJ57799
  • receptor-type tyrosine-protein phosphatase epsilon
  • DKFZp313F1310
  • protein tyrosine phosphatase, receptor type, epsilon polypeptide
  • EC 3.1.3.48
  • protein tyrosine phosphatase epsilon
  • Protein-tyrosine phosphatase epsilon
  • R-PTP-EPSILON
  • PTPE
  • HPTPE
  • protein tyrosine phosphatase, receptor type, E

Research Areas for PTP epsilon

Find related products by research area and learn more about each of the different research areas below.

GPCR
Protein Phosphatase
Tyrosine Kinases

PTMs for PTP epsilon

Learn more about PTMs related to PTP epsilon.

Phosphorylation
Dephosphorylation
Cleavage
Methylation

Bioinformatics Tool for PTP epsilon

Discover related pathways, diseases and genes to PTP epsilon. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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