PSMB7 Products

Description

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).

Bioinformatics

Entrez	5695 Human 19177 Mouse 85492 Rat
Uniprot	Q5TBG6 Human
Product By Gene ID	5695
Alternate Names	Macropain Chain Z Proteasome Subunit Z PSMB7 Z

Research Areas for PSMB7

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Ubiquitin Proteasome Pathway