Proteasome 26S S5 Products

Description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator base.

Bioinformatics

Entrez	5711 Human
Uniprot	AAH14478 Human AAH14478.1 Human NM_005047 Human NP_005038.1 Human Q16401 Human
Product By Gene ID	5711
Alternate Names	KIAA007226S proteasome non-ATPase regulatory subunit 5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5,26S proteasome subunit S5B S5BMGC23145,26S protease subunit S5 basic

Research Areas for Proteasome 26S S5

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Ubiquitin Proteasome Pathway