Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.
Bioinformatics
| Product By Gene ID |
5690 |
| Alternate Names |
- EC 3.4.25.1
- HC7-I
- Macropain subunit C7-I
- MGC104215
- MGC126885
- multicatalytic endopeptidase complex subunit C7-1
- Multicatalytic endopeptidase complex subunit C7-I
- proteasome (prosome, macropain) subunit, beta type, 2
- Proteasome 20S beta2
- proteasome beta 2 subunit
- Proteasome component C7-I
- proteasome subunit beta type-2
- proteasome subunit, beta type, 2
- PSMB2
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