Proteasome 20S alpha 5 Products

Antibodies
Proteasome 20S alpha 5 Antibo ...
Proteasome 20S alpha 5 Antibody
NBP1-86838
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Proteasome 20S alpha 5 Antibo ...
Proteasome 20S alpha 5 Antibody
NBP1-32387
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Proteasome 20S alpha 5 Antibo ...
Proteasome 20S alpha 5 Antibody
NBP1-86839
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Proteins
Proteasome 20S alpha 5 Recomb ...
Proteasome 20S alpha 5 Recombinant...
NBP1-86839PEP
Species: Hu
Applications: AC
Proteasome 20S alpha 5 Recomb ...
Proteasome 20S alpha 5 Recombinant...
NBP1-86838PEP
Species: Hu
Applications: AC
Proteasome 20S alpha 5 Recomb ...
Proteasome 20S alpha 5 Recombinant...
NBP1-86837PEP
Species: Hu
Applications: AC
RNAi
Proteasome 20S alpha 5 RNAi
Proteasome 20S alpha 5 RNAi
H00005686-R01
Species: Hu

Description

Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signaling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes, and the endoplasmic reticulum. The 26S proteasome is an ATP-dependent, multisubunit (~31), barrel-shaped molecular machine with an apparent molecular weight of ~2.5 MDa. It consists of a 20S proteolytic core complex which is crowned at one or both ends by 19S regulatory subunit complexes. The 19S regulatory subunits recognize ubiquitinated proteins and play an essential role in unfolding and translocating targets into the lumen of the 20S subunit. An enzymatic cascade is responsible for the attachment of multiple ubiquitin molecules to lysine residues of proteins targeted for degradation. Several genetic diseases are associated with defects in the ubiquitin-proteasome pathway. Some examples of affected proteins include those linked to cystic fibrosis, Angelman's syndrome, and Liddle syndrome.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 5686
Alternate Names
  • MGC117302
  • proteasome subunit zeta
  • FLJ42315
  • proteasome subunit alpha type-5
  • PSC5
  • proteasome component 5
  • EC 3.4.25.1
  • proteasome alpha 5 subunit
  • Proteasome zeta chain
  • macropain subunit zeta
  • Multicatalytic endopeptidase complex zeta chain
  • MGC125804
  • Macropain zeta chain
  • MGC125803
  • ZETA
  • MGC125802
  • proteasome (prosome, macropain) subunit, alpha type, 5

Pathways for Proteasome 20S alpha 5

View related products by pathway and learn more about each of the pathways below.

Sensitization

Research Areas for Proteasome 20S alpha 5

Find related products by research area and learn more about each of the different research areas below.

Core ESC-Like Genes
Stem Cell Markers

PTMs for Proteasome 20S alpha 5

Learn more about PTMs related to Proteasome 20S alpha 5.

Phosphorylation

Bioinformatics Tool for Proteasome 20S alpha 5

Discover related pathways, diseases and genes to Proteasome 20S alpha 5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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