Prolactin R Products

Description

Prolactin (PRL) is a hormone involved in a variety of important functions including ion transport and osmoregulation, stimulation of milk, protein synthesis as well as the regulation of numerous reproductive functions. PRL exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane PRL receptor. Immunoreactive PRL receptor, a member of the cytokine receptor family, varies in size (short and long forms) with tissue source and species, from ~40 kDa to 100 kDa. The PRL receptor consists of at least three separate domains: an extracellular region with 5 cysteines which contains the prolactin binding site, a single transmembrane domain and a cytoplasmic region, the length of which appears to influence ligand binding and regulate cellular function.

Bioinformatics

Entrez	100009046 Rabbit 24684 Rat 5618 Human
Uniprot	NP_000940 Human NP_000940.1 Human P05710 Rat P16471 Human
Product By Gene ID	5618
Alternate Names	delta 4-delta 7/11 truncated prolactin receptor delta 4-SF1b truncated prolactin receptor hPRL receptor hPRLrI PRL-R prolactin receptor delta 7/11 prolactin receptor secreted prolactin binding protein

Research Areas for Prolactin R

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