proBDNF Products

Description

FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted.

Bioinformatics

Entrez	12064 Mouse 24225 Rat
Uniprot	P23560
Product By Gene ID	627
Alternate Names	abrineurin brain-derived neurotrophic factor MGC34632 neurotrophin

Research Areas for proBDNF

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Immunology
Neuroscience