PRDM11 Products

Antibodies
PRDM11 Antibody
PRDM11 Antibody
NBP2-30650
Species: Hu, Mouse, Rat
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
PRDM11 Antibody
PRDM11 Antibody
NB100-1525
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Proteins
PRDM11 Recombinant Protein An ...
PRDM11 Recombinant Protein Antigen
NBP2-30650PEP
Species: Hu
Applications: AC

Description

The newly discovered family of PR domain genes is involved in tumorigenesis. Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein interacting zinc finger gene RIZ1 is a tumor suppressor gene and a FOUNDING member of the PR domain family. RIZ1 inactivation is commonly found in many types of human cancers and occurs through loss of mRNA expression, frame shift mutation, chromosomal deletion, and missense mutation.

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 56981
Alternate Names
  • PR-domain containing protein 11
  • PFM8PR domain-containing protein 11
  • PR domain containing 11

Bioinformatics Tool for PRDM11

Discover related pathways, diseases and genes to PRDM11. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.