PRCC Products

Antibodies
PRCC Antibody
PRCC Antibody
NBP1-87153
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PRCC Antibody
PRCC Antibody
25180002
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
PRCC Antibody
PRCC Antibody
NBP1-87152
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PRCC Overexpression Lysate (N ...
PRCC Overexpression Lysate (Native)
NBL1-14730
Applications: WB
Proteins
Recombinant Human PRCC Protei ...
Recombinant Human PRCC Protein
H00005546-P01
Species: Hu
Applications: WB, ELISA, PA
PRCC Recombinant Protein Anti ...
PRCC Recombinant Protein Antigen
NBP1-87153PEP
Species: Hu
Applications: AC
PRCC Recombinant Protein Anti ...
PRCC Recombinant Protein Antigen
NBP1-87152PEP
Species: Hu
Applications: AC

Description

In a subset of papillary renal cell carcinomas, a t(X;1)(p11;q21) chromosome translocation has been repeatedly reported and is thought to be the cause of the cancer. As a result of the translocation, the transcription factor TFE3 on the X chromosome becomes fused to the PRCC (papillary renal cell carcinoma translocation-associated) gene on chromosome 1. The fused gene results in the fusion of N-terminal proline-rich region of the protein encoded by this gene to the entire TFE3 protein. This protein has been shown to interact with the mitotic checkpoint protein MAD2B, which suggests that the dominant-negative effect of the fusion protein with TFE3 may lead to a mitotic checkpoint defect.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 5546
Alternate Names
  • TPRC
  • proline-rich protein PRCC
  • Papillary renal cell carcinoma translocation-associated gene protein
  • RCCP1MGC4723
  • MGC17178
  • papillary renal cell carcinoma (translocation-associated)

PTMs for PRCC

Learn more about PTMs related to PRCC.

Phosphorylation

Bioinformatics Tool for PRCC

Discover related pathways, diseases and genes to PRCC. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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