PRC1 Products

Antibodies
PRC1 Antibody
PRC1 Antibody
NBP1-88856
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PRC1 Antibody
PRC1 Antibody
NBP2-19925
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PRC1 Overexpression Lysate (N ...
PRC1 Overexpression Lysate (Native)
NBL1-14729
Applications: WB
Proteins
PRC1 Recombinant Protein
PRC1 Recombinant Protein
H00009055-P01
Species: Hu
Applications: WB, ELISA, PA
PRC1 Recombinant Protein Anti ...
PRC1 Recombinant Protein Antigen
NBP1-88856PEP
Species: Hu
Applications: AC
RNAi
PRC1 RNAi
PRC1 RNAi
H00009055-R01
Species: Hu
PRC1 RNAi
PRC1 RNAi
H00009055-R02
Species: Hu
PRC1 RNAi
PRC1 RNAi
H00009055-R03
Species: Hu

Description

Novel human protein Protein regulator of cytokinesis 1 (PRC1) is involved in cytokinesis. PRC1 is a good substrate for several CDKs in vitro and is phosphorylated in vivo at sites that are phosphorylated by CDK in vitro, strongly suggesting that PRC1 is an in vivo CDK substrate. PRC1 protein levels are high during S and G2/M and drop dramatically after cells exit mitosis and enter G1. PRC1 is a nuclear protein in interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis (1). PRC1, a mitotic spindle-associated Cdk substrate that is essential to cell cleavage, is a microtubule binding and bundling protein both in vivo and in vitro. Over expression of PRC1 extensively bundles interphase microtubules, but does not affect early mitotic spindle organization (2). PRC1 has been shown to down-regulate the GAP activity of MgcRac-GAP during the metaphase and thereby contributes to the correct formation of the spindle (3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 9055
Alternate Names
  • protein regulating cytokinesis 1
  • anaphase spindle elongation 1 homolog
  • MGC3669
  • MGC1671
  • ASE1
  • protein regulator of cytokinesis 1

Research Areas for PRC1

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Mitotic Regulators
Phospho-Specific

Bioinformatics Tool for PRC1

Discover related pathways, diseases and genes to PRC1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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