PRAS40 Products

Antibodies
PRAS40 Antibody (1211A) [Unco ...
PRAS40 Antibody (1211A) [Unconjuga...
MAB68901
Species: Hu
Applications: WB
Host: Rabbit Monoclonal
PRAS40 Antibody (660928) [Unc ...
PRAS40 Antibody (660928) [Unconjug...
MAB6408
Species: Hu
Applications: WB, Simple Western, ICC
Host: Mouse Monoclonal
PRAS40 [p thr246] Antibody (7 ...
PRAS40 [p thr246] Antibody (760502)
MAB6890
Species: Hu, Mu
Applications: WB, ICC
Host: Mouse Monoclonal
Lysates
PRAS40 Overexpression Lysate ...
PRAS40 Overexpression Lysate (Native)
NBP2-10916
Applications: WB
PRAS40 Overexpression Lysate ...
PRAS40 Overexpression Lysate (Native)
NBP2-06037
Applications: WB
PRAS40 Overexpression Lysate ...
PRAS40 Overexpression Lysate (Native)
NBP2-10917

Description

Proline Rich Akt Substrate (PRAS40) is a 40 kDa substrate of Akt. Akt and PRAS40 can be found in the phosphoinositide 3 kinase (PI3K) pathway, which plays a role in glucose uptake, cell growth, and apoptosis inhibition. PRAS40 is a 14-3-3 binding protein that reacts with insulin, but whose precise function is not yet known. It may bind SH3 and WW domain containing proteins resulting in a change of function. Activated Akt phosphorylates PRAS40 on threonine 246. Mutation of PRAS40 threonine 246 has been shown to be apoptotic.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 84335
Alternate Names
  • proline-rich AKT1 substrate 1,40 kDa proline-rich AKT substrate
  • MGC2865
  • 40 kDa
  • AKT1 substrate 1 (proline-rich)

Research Areas for PRAS40

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Autophagy
Cancer
Growth and Development
Lipid and Metabolism
mTOR Pathway
Neuronal Cell Markers
Neuroscience
Phospho-Specific
Tumor Suppressors

PTMs for PRAS40

Learn more about PTMs related to PRAS40.

Phosphorylation

Bioinformatics Tool for PRAS40

Discover related pathways, diseases and genes to PRAS40. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related PRAS40 Blog Posts

Check out the latest blog posts on PRAS40.
Mapping Signal Transduction with mTOR Antibodies
The protein encoded by mTOR (mammalian target of rapamycin), also known as dTOR in Drosophila, belongs to a family of phosphatidylinositol kinase-related kinases. These kinases regulate fundamental processes of cell growth, proliferation, metabolism...    Read more.
Read more PRAS40 related blogs.