PRAME Products

Antibodies
PRAME Antibody
PRAME Antibody
NBP1-85418
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
PRAME Antibody
PRAME Antibody
NBP2-23670
Species: Hu, Canine, Equine, Primate
Applications: WB, Simple Western
Host: Rabbit Polyclonal
PRAME Antibody
PRAME Antibody
H00023532-D01
Species: Hu
Applications: WB, ELISA, ICC/IF, IP, IF
Host: Rabbit Polyclonal
Antibody Pairs
PRAME Antibody Pair
PRAME Antibody Pair
H00023532-PW1
Species: Hu
Applications: WB, IP
Lysates
PRAME Overexpression Lysate ( ...
PRAME Overexpression Lysate (Denat...
H00023532-T01
Species: Hu
Applications: WB
PRAME Overexpression Lysate ( ...
PRAME Overexpression Lysate (Native)
NBL1-14725
Applications: WB
PRAME Overexpression Lysate ( ...
PRAME Overexpression Lysate (Native)
NBL1-14724
Applications: WB
Proteins
PRAME Recombinant Protein
PRAME Recombinant Protein
H00023532-P01
Species: Hu
Applications: WB, ELISA, PA

Description

PRAME encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Recent data from Epping et.al., (Cell, Vol. 122: 835) suggest that overexpression of PRAME frequently observed in human cancers confers growth or survival advantages by antagonizing RAR signaling.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 23532
Alternate Names
  • Opa-interacting protein OIP4
  • Preferentially expressed antigen of melanoma
  • melanoma antigen preferentially expressed in tumors
  • Opa-interacting protein 4
  • cancer/testis antigen 130
  • MAPEOIP4CT130
  • OIP-4
  • preferentially expressed antigen in melanoma

Research Areas for PRAME

Find related products by research area and learn more about each of the different research areas below.

Cancer

PTMs for PRAME

Learn more about PTMs related to PRAME.

Methylation
Demethylation
Myristoylation

Bioinformatics Tool for PRAME

Discover related pathways, diseases and genes to PRAME. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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