Species: Hu
Applications: WB, ELISA, ICC/IF, IP
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, IP
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
PP2A is a major serine/threonine phosphatase that is implicated in the negative control of cell cycle progression. It is a trimeric holoenzyme that is comprised of a catalytic, structural, and regulatory subunit. PPP2R3B is a regulatory subunit of PP2A. The regulatory subunits of PP2A are grouped into 3 families: B/PR55, B'/PR61, and B''/PR72. PPP2R3B encodes a 48 kDa B'' regulatory subunit. PPP2R3B and PP2A, in association with Cdc6, are implicated in cell cycle control via phosphatase activity targeted at DNA replication machinery.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human Human |
Product By Gene ID |
28227 |
Alternate Names |
- FLJ60425
- NY-REN-8 antigen
- NYREN8
- PP2A subunit B isoform PR48
- PP2A, subunit B, PR48 isoform
- PPP2R3L
- PPP2R3LY
- PR48
- protein phosphatase 2 (formerly 2A), regulatory subunit B'', beta
- protein phosphatase 2, regulatory subunit B'', beta
- Protein phosphatase 2A 48 kDa regulatory subunit
- serine/threonine protein phosphatase 2A, 48kDa regulatory subunit B
- serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta
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Research Areas for PR48
Find related products by research area and learn more about each of the different research areas below.
Cell Cycle and Replication