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The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2008]
![SDS-Page PPT1 [Unconjugated]](http://images.novusbio.com/fullsize/11661-pt_recombinant-human-ppt1-ha-tag-his-tag-protein-cf-sds-page-31120259129..jpg)
