PPP2R2B Products

Description

Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Bioinformatics

Product By Gene ID

5521

Alternate Names

B55BETA FLJ95686 MGC24888 PP2A subunit B isoform B55-beta PP2A subunit B isoform beta PP2A subunit B isoform PR55-beta PP2A subunit B isoform R2-beta PP2A, subunit B, B-beta isoform PP2AB55BETA PP2ABBETA PP2APR55B PP2APR55BETA PR2AB55BETA PR2ABBETA PR2APR55BETA PR52B PR55BETA PR55-BETA protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform protein phosphatase 2, regulatory subunit B, beta SCA12 serine/threonine protein phosphatase 2A, 55 kDa regulatory subunit B, betaisoform serine/threonine protein phosphatase 2A, neuronal isoform serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B betaisoform spinocerebellar ataxia 12

Research Areas for PPP2R2B

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