PPP2R2B Products

Description

The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in the 5' UTR of this gene may cause a rare form of autosomal dominant spinocerebellar ataxia 12 (SCA12).

Bioinformatics

Entrez	5521 Human 72930 Mouse
Uniprot	AAH31790 Human AAH31790.1 Human NM_181675 Human NP_001120853 Human NP_004567 Human NP_004567.1 Human NP_858060 Human Q00005 Human
Product By Gene ID	5521
Alternate Names	B55BETA FLJ95686 MGC24888 PP2A subunit B isoform B55-beta PP2A subunit B isoform beta PP2A subunit B isoform PR55-beta PP2A subunit B isoform R2-beta PP2A, subunit B, B-beta isoform PP2AB55BETA PP2ABBETA PP2APR55B PP2APR55BETA PR2AB55BETA PR2ABBETA PR2APR55BETA PR52B PR55BETA PR55-BETA protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform protein phosphatase 2, regulatory subunit B, beta SCA12 serine/threonine protein phosphatase 2A, 55 kDa regulatory subunit B, betaisoform serine/threonine protein phosphatase 2A, neuronal isoform serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B betaisoform spinocerebellar ataxia 12

Research Areas for PPP2R2B

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Stem Cell Markers