PPHLN1 Products

Description

The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]. Transcript Variant: This variant (5) has multiple differences compared to variant 1. The resulting isoform (5) has distinct N- and C-termini, as compared to isoform 1.

Bioinformatics

Product By Gene ID	51535
Alternate Names	Gastric cancer antigen Ga50 HSPC232 MGC48786 periphilin 1 periphilin-1

Research Areas for PPHLN1

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Cell Cycle and Replication