Porimin Products

Description

This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.

Bioinformatics

Entrez	114908 Human
Uniprot	NP_443164
Product By Gene ID	114908
Alternate Names	KCT3 KCT-3 KCT3keratinocytes associated transmembrane protein 3 Keratinocytes-associated transmembrane protein 3 Porimin PORIMINporimin pro oncosis receptor inducing membrane injury Pro-oncosis receptor inducing membrane injury serine/threonine-rich receptor TMEM123 transmembrane protein 123PORMIN

Research Areas for Porimin

Find related products by research area and learn more about each of the different research areas below.

Apoptosis