Porimin Products

Description

Porimin was identified by a monoclonal antibody developed by immunizing mice with apoptotic cells. One of these antibodies, designated anti-Porimin (for pro-oncosis receptor inducing membrane injury), was found to directly induce a unique type of cell death in Jurkat cells by binding to a 110-kDa cell surface receptor on Jurkat cells. Anti-Porimin-mediated cell death was preceded by cell aggregation, formation of plasma membrane pores, and the appearance of membrane blebs. More important, these cells show neither DNA fragmentation nor apoptotic bodies, but display lethal damage of the cell membrane.

Bioinformatics

Entrez	114908 Human
Uniprot	NP_443164 Human NP_443164.2 Human Q8N131 Human
Product By Gene ID	114908
Alternate Names	KCT-3 KCT3keratinocytes associated transmembrane protein 3 Keratinocytes-associated transmembrane protein 3 PORIMINporimin pro oncosis receptor inducing membrane injury Pro-oncosis receptor inducing membrane injury serine/threonine-rich receptor transmembrane protein 123PORMIN

Research Areas for Porimin

Find related products by research area and learn more about each of the different research areas below.

Apoptosis