Species: Hu, Mu, Rt, Bv, Ch
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Mouse Monoclonal
Species: Rt, Pm-Or, RM
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Porimin was identified by a monoclonal antibody developed by immunizing mice with apoptotic cells. One of these antibodies, designated anti-Porimin (for pro-oncosis receptor inducing membrane injury), was found to directly induce a unique type of cell death in Jurkat cells by binding to a 110-kDa cell surface receptor on Jurkat cells. Anti-Porimin-mediated cell death was preceded by cell aggregation, formation of plasma membrane pores, and the appearance of membrane blebs. More important, these cells show neither DNA fragmentation nor apoptotic bodies, but display lethal damage of the cell membrane.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human |
Product By Gene ID |
114908 |
Alternate Names |
- KCT-3
- KCT3keratinocytes associated transmembrane protein 3
- Keratinocytes-associated transmembrane protein 3
- PORIMINporimin
- pro oncosis receptor inducing membrane injury
- Pro-oncosis receptor inducing membrane injury
- serine/threonine-rich receptor
- transmembrane protein 123PORMIN
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Research Areas for Porimin
Find related products by research area and learn more about each of the different research areas below.
Apoptosis