Polycystin-1/PKD1 Products

Antibodies
Polycystin-1/PKD1 Antibody [U ...
Polycystin-1/PKD1 Antibody [Unconj...
AF6270
Species: Hu
Applications: ICC
Host: Sheep Polyclonal
Polycystin-1/PKD1 Antibody
Polycystin-1/PKD1 Antibody
NBP1-19424
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal

Description

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (alpha, betaI, betaII and gamma) and novel (n) PKC isoforms (delta, episilon, zeta, eta and theta). Patterns of expression for each PKC isoform differs among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC delta and episilon are independent of Ca++. On the other hand, nPKC delta and episilon, as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activities.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Product By Gene ID 5310
Alternate Names
  • Autosomal dominant polycystic kidney disease 1 protein
  • transient receptor potential cation channel, subfamily P, member 1
  • TRPP1
  • polycystin-1
  • Pc-1
  • polycystin 1
  • PBP
  • polycystic kidney disease-associated protein
  • polycystic kidney disease 1 (autosomal dominant)

Research Areas for Polycystin-1/PKD1

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Phospho-Specific

Bioinformatics Tool for Polycystin-1/PKD1

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