POLR3H Products

Description

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleosidetriphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Actsas nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves astemplate for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encodedRNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway

Bioinformatics

Entrez	171568 Human
Uniprot	B0QYH9 Human CAK54440.1 Human NM_001018052 Human NM_138338 Human NP_001018060 Human Q9Y535 Human
Product By Gene ID	171568
Alternate Names	DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide DNA-directed RNA polymerase III subunit H DNA-directed RNA polymerase III subunit RPC8 KIAA1665MGC29654 MGC111097 polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) RNA nucleotidyltransferase (DNA-directed) RNA polymerase III subunit 22.9 kDa subunit RNA polymerase III subunit C8 RNA polymerase III subunit RPC8 RPC8RPC22.9