POLR1B Products

Antibodies
POLR1B Antibody (4H6)
POLR1B Antibody (4H6)
H00084172-M10
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
POLR1B Antibody
POLR1B Antibody
NBP1-53191
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
POLR1B Overexpression Lysate ...
POLR1B Overexpression Lysate (Native)
NBL1-14574
Applications: WB
Proteins
POLR1B Partial Recombinant Pr ...
POLR1B Partial Recombinant Protein
H00084172-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
POLR1B RNAi
POLR1B RNAi
H00084172-R01
Species: Hu

Description

POLR1B, also known as DNA-directed RNA polymerase I subunit RPA2, has a 1,135 amino acid long isoform that is approximately 128kDa, and a short 1,079 amino acid isoform that is approximately 121kDa. POLR1B is a RNA polymerase that is localized to the nucleolus. POLR1B is the second largest fundamental element of pol I, which is responsible for the production of ribosomal RNA. Current research on POLR1B is being performed in relation to several diseases and disorders including pneumonia, malaria and tuberculosis. POLR1B has also been shown to have interactions with Histone cluster 1 H4/A, H4/B, H4/C, H4/D and H4/E in pathways such as RNA Polymerase I transcription and RNA Polymerase III transcription.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 84172
Alternate Names
  • RPA116
  • DNA-directed RNA polymerase I subunit RPA2
  • RPA135
  • DNA-directed RNA polymerase I 135kDa polypeptide
  • Rpo1-2
  • MGC131780
  • RPA2
  • EC 2.7.7.6
  • FLJ21921
  • RNA polymerase I subunit 2
  • FLJ10816
  • DNA-directed RNA polymerase I 135 kDa polypeptide
  • polymerase (RNA) I polypeptide B, 128kDa

Diseases related to POLR1B

Discover more about diseases related to POLR1B.

Leukemia, Myelocytic, Acute
Malignant Neoplasms
Myeloid Leukemia
Therapy-related Acute Myeloid Leukemia
Leukemia

Pathways for POLR1B

View related products by pathway and learn more about each of the pathways below.

Granulocyte Differentiation
Cell Cycle
Dna Repair
Pathogenesis
Chromatin Remodeling

Bioinformatics Tool for POLR1B

Discover related pathways, diseases and genes to POLR1B. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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