POGZ Products

Antibodies
POGZ Antibody
POGZ Antibody
NBP1-83004
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
POGZ Antibody
POGZ Antibody
NBP1-83005
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
POGZ Antibody
POGZ Antibody
H00023126-B01P
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Polyclonal
Lysates
POGZ Overexpression Lysate (D ...
POGZ Overexpression Lysate (Denatu...
H00023126-T02
Applications: WB
POGZ Overexpression Lysate (D ...
POGZ Overexpression Lysate (Denatu...
H00023126-T01
Applications: WB
Proteins
POGZ Recombinant Protein Anti ...
POGZ Recombinant Protein Antigen
NBP1-83005PEP
Species: Hu
Applications: AC
POGZ Recombinant Protein Anti ...
POGZ Recombinant Protein Antigen
NBP1-83004PEP
Species: Hu
Applications: AC
RNAi
POGZ RNAi
POGZ RNAi
H00023126-R02
Species: Hu
POGZ RNAi
POGZ RNAi
H00023126-R01
Species: Hu
POGZ RNAi
POGZ RNAi
H00023126-R03
Species: Hu

Description

Pogz is a zinc-finger protein containing at least 8 C2H2 zinc fingers, a CENP-B (centromere protein-B) domain, and a DDE domain found in the bacterial transposase/retroviral integrase family. Members of this family of integrases share structural homologies and show similar catalytic activity to the RAG1 and RAG2 proteins that initiate V(D)J recombination in lymphoid progenitors. Mouse Pogz has a human homolog with a base pair similarity of 90% and amino acid similarity of 93% for the full length protein. In humans at least 3 variants have been predicted and they are all similar at the Nterminus. A number of expressed sequence tags (ESTs) cloned from murine undifferentiated ES cells and Lin-/c-Kit+/Sca-1+ hematopoietic stem cell cDNA libraries correspond to the Pogz gene, further underlining an important function for this gene in stem cells. In mice, deletion of the gene in all tissues early in embryogenesis has been shown to be lethal.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 23126
Alternate Names
  • Zinc finger protein 280E
  • putative protein product of Nbla00003
  • Suppressor of hairy wing homolog 5
  • ZNF280EZNF635m
  • SUHW5MGC71543
  • KIAA0461ZNF635
  • Zinc finger protein 635
  • pogo transposable element with ZNF domain

Diseases related to POGZ

Discover more about diseases related to POGZ.

Immunologic Deficiency Syndromes
Hiv Infections

Pathways for POGZ

View related products by pathway and learn more about each of the pathways below.

Regulation Of Localization
Mitosis
M Phase
Localization

Bioinformatics Tool for POGZ

Discover related pathways, diseases and genes to POGZ. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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