PML Protein Products

Antibodies
PML Protein Antibody
PML Protein Antibody
NB100-59787
Species: Hu, Mu, Primate, Monkey
Applications: WB, ICC/IF, IHC, IHC-P, IP, PLA
Host: Rabbit Polyclonal
PML Protein Antibody
PML Protein Antibody
NB100-59788
Species: Hu, Primate, Monkey
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
PML Protein Antibody
PML Protein Antibody
NBP1-87783
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PML Protein Overexpression Ly ...
PML Protein Overexpression Lysate ...
NBP2-05900
Applications: WB
Proteins
PML Protein Partial Recombina ...
PML Protein Partial Recombinant Pr...
H00005371-Q01
Species: Hu
Applications: WB, ELISA, PA
PML Protein Recombinant Prote ...
PML Protein Recombinant Protein An...
NBP1-87783PEP
Species: Hu
Applications: AC
RNAi
PML Protein RNAi
PML Protein RNAi
H00005371-R04
Species: Hu
Applications: RNAi, RNAi SP
PML Protein RNAi
PML Protein RNAi
H00005371-R02
Species: Hu
Applications: RNAi, RNAi SP
PML Protein RNAi
PML Protein RNAi
H00005371-R03
Species: Hu
Applications: RNAi, RNAi SP

Description

PML Protein is encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 5371
Alternate Names
  • Tripartite motif-containing protein 19
  • tripartite motif protein TRIM19
  • Promyelocytic leukemia protein
  • TRIM19promyelocytic leukemia, inducer of
  • RNF71probable transcription factor PML
  • MYLPP8675
  • RING finger protein 71
  • promyelocytic leukemia

Research Areas for PML Protein

Find related products by research area and learn more about each of the different research areas below.

Cancer
Zinc Finger

Bioinformatics Tool for PML Protein

Discover related pathways, diseases and genes to PML Protein. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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