PLA2G4C Products

Antibodies
PLA2G4C Antibody
PLA2G4C Antibody
NBP1-85480
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PLA2G4C Antibody
PLA2G4C Antibody
H00008605-B01P
Species: Hu
Applications: WB, ELISA
Host: Mouse Polyclonal
Lysates
PLA2G4C Overexpression Lysate ...
PLA2G4C Overexpression Lysate (Den...
H00008605-T01
Species: Hu
Applications: WB
PLA2G4C Overexpression Lysate ...
PLA2G4C Overexpression Lysate (Nat...
NBL1-14475
Applications: WB
Proteins
PLA2G4C Recombinant Protein
PLA2G4C Recombinant Protein
H00008605-P01
Species: Hu
Applications: WB, ELISA, PA
PLA2G4C Recombinant Protein A ...
PLA2G4C Recombinant Protein Antigen
NBP1-85480PEP
Species: Hu
Applications: AC

Description

PLA2G4C, also known as Cytosolic phospholipase A2 gamma, has 3 isoforms, a 541 amino acid isoform that is 61 kDa, a 527 amino acid isoform that is 59 kDa and a 551 amino acid isoform that is 62 kDa; highly expressed in heart and skeletal muscle; hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids, both of which serve as precursors in the production of signaling molecules has been shown to be a calcium-independent and membrane bound enzyme, and has a preference for arachidonic acid at the sn-2 position of phosphatidylcholine as compared with palmitic acid. This protein has being studied for its involvement in oligodendroglioma, ovarian cancer, breast cancer, schizophrenia, and neuronitis. PLA2G4C protein has been observed with relation to S100A10, MBOAT2, GPCPD1, LPCAT1, and LPCAT2 in immune response CD16 signaling in NK cells, development Leptin signaling via JAK/STAT and MAPK cascades, development Alpha-2 adrenergic receptor activation of ERK, immune response CCR3 signaling in eosinophils, neurophysiological process PGE2-induced pain processing, chemokine signaling, DHA signaling, VEGF family ligands and receptor interactions, antioxidant action of vitamin-C, LDL oxidation in atherogenesis, phospholipases, acyl chain remodelling of PE, metabolism, acyl chain remodelling of PC, hydrolysis of LPC, and phospholipid metabolism pathways.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 8605
Alternate Names
  • DKFZp586C0423
  • EC 3.1.1.4
  • CPLA2-gamma
  • cytosolic phospholipase A2 gamma
  • Phospholipase A2 group IVC
  • FLJ44164
  • cPLA2-gamma
  • FLJ42247
  • phospholipase A2, group IVC (cytosolic, calcium-independent)

PTMs for PLA2G4C

Learn more about PTMs related to PLA2G4C.

Methylation

Bioinformatics Tool for PLA2G4C

Discover related pathways, diseases and genes to PLA2G4C. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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