PKC epsilon Products

Description

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.

Bioinformatics

Entrez	18754 Mouse 29340 Rat 5581 Human
Uniprot	NM_005400 Human NP_005391 Human P09216 Rat P16054 Mouse Q02156 Human
Product By Gene ID	5581
Alternate Names	EC 2.7.11 EC 2.7.11.13 MGC125656 nPKC-epsilon PKCEMGC125657 protein kinase C epsilon type protein kinase C, epsilon

Research Areas for PKC epsilon

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Phospho-Specific
Signal Transduction