PILR-alpha Products

Antibodies
PILR-alpha Antibody (462415)
PILR-alpha Antibody (462415)
MAB6484
Species: Hu
Applications: WB
Host: Mouse Monoclonal
PILR-alpha Antibody
PILR-alpha Antibody
AF4318
Species: Mu
Applications: WB, Flow
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Lysates
PILR-alpha Overexpression Lys ...
PILR-alpha Overexpression Lysate (...
NBP2-04980
Applications: WB
Proteins
PILR-alpha Recombinant Protei ...
PILR-alpha Recombinant Protein
H00029992-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
PILR-alpha RNAi
PILR-alpha RNAi
H00029992-R04
Species: Hu
Applications: RNAi, RNAi SP
PILR-alpha RNAi
PILR-alpha RNAi
H00029992-R05
Species: Hu
Applications: RNAi, RNAi SP
PILR-alpha RNAi
PILR-alpha RNAi
H00029992-R06
Species: Hu
Applications: RNAi, RNAi SP

Description

Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described. (provided by RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 29992
Alternate Names
  • paired immunoglobulin-like type 2 receptor alpha
  • Inhibitory receptor PILR-alpha
  • paired immunoglobulin-like receptor alpha
  • Cell surface receptor FDF03
  • paired immunoglobin-like receptor alpha
  • FDF03
  • inhibitory receptor PILRalpha
  • paired immunoglobin-like type 2 receptor alpha

Research Areas for PILR-alpha

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

PTMs for PILR-alpha

Learn more about PTMs related to PILR-alpha.

Phosphorylation
Glycosylation
Reduction
Dephosphorylation

Bioinformatics Tool for PILR-alpha

Discover related pathways, diseases and genes to PILR-alpha. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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