PGAM2 Products

Description

Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X. (provided by RefSeq)

Bioinformatics

Uniprot	P15259 Human NP_000281.2 Human NM_000290 Human
Product By Gene ID	5224
Alternate Names	EC 5.4.2.4 BPG-dependent PGAM 2 EC 3.1.3.13 Phosphoglycerate mutase isozyme M phosphoglycerate mutase 2 Muscle-specific phosphoglycerate mutase PGAMMMGC88743 PGAM-MGSD10 EC 5.4.2.1 phosphoglycerate mutase 2 (muscle)

Diseases related to PGAM2

Discover more about diseases related to PGAM2.

Limb Deformities, Congenital
Myopathy
Glycogen Storage Disease
Storage Disease
Greig Cephalopolysyndactyly Syndrome
Muscle Cramp
Myocardial Ischemia
Glycogen Storage Disease Type Ii
Craniofacial Abnormalities
Hypoxia
Inflammatory Response
Muscle Necrosis
Fibrosis
Neoplasms
Maturity Onset Diabetes Mellitus In Young
Refractory Neutropenia

Pathways for PGAM2

View related products by pathway and learn more about each of the pathways below.

Glycolysis
Methylation
Cell Proliferation
Translation
Circadian Rhythm
Pathogenesis
Inflammatory Response

PTMs for PGAM2

Learn more about PTMs related to PGAM2.

Methylation

Bioinformatics Tool for PGAM2

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